Mahomes throws 5 TDs, Chiefs hammer Cardinals 44-21
Kansas City Chiefs safety Justin Reid (20) kicks an extra point against the Arizona Cardinals during the first half of an NFL football game, Sunday, Sept. 11, 2022, in Glendale, Ariz. (AP Photo/Ross D. Franklin)

Kansas City Chiefs safety Justin Reid (20) kicks an extra point against the Arizona Cardinals during the first half of an NFL football game, Sunday, Sept. 11, 2022, in Glendale, Ariz. (AP Photo/Ross D. Franklin)

Sep. 11, 2022 05:42 PM EDT
Arizona Cardinals quarterback Kyler Murray (1) hands off to Arizona Cardinals running back James Conner (6) for a touchdown run against the Kansas City Chiefs during the first half of an NFL football game, Sunday, Sept. 11, 2022, in Glendale, Ariz. (AP Photo/Ross D. Franklin)

Arizona Cardinals quarterback Kyler Murray (1) hands off to Arizona Cardinals running back James Conner (6) for a touchdown run against the Kansas City Chiefs during the first half of an NFL football game, Sunday, Sept. 11, 2022, in Glendale, Ariz. (AP Photo/Ross D. Franklin)

Sep. 11, 2022 05:18 PM EDT
Arizona Cardinals running back James Conner (6) and quarterback Kyler Murray (1) attempt to recover a botched snap during the first half of an NFL football game against the Kansas City Chiefs, Sunday, Sept. 11, 2022, in Glendale, Ariz. (AP Photo/Ross D. Franklin)

Arizona Cardinals running back James Conner (6) and quarterback Kyler Murray (1) attempt to recover a botched snap during the first half of an NFL football game against the Kansas City Chiefs, Sunday, Sept. 11, 2022, in Glendale, Ariz. (AP Photo/Ross D. Franklin)

Sep. 11, 2022 05:09 PM EDT
Arizona Cardinals quarterback Kyler Murray (1) throws against the Kansas City Chiefs during the first half of an NFL football game, Sunday, Sept. 11, 2022, in Glendale, Ariz. (AP Photo/Ross D. Franklin)

Arizona Cardinals quarterback Kyler Murray (1) throws against the Kansas City Chiefs during the first half of an NFL football game, Sunday, Sept. 11, 2022, in Glendale, Ariz. (AP Photo/Ross D. Franklin)

Sep. 11, 2022 05:03 PM EDT
Kansas City Chiefs head coach Andy Reid watches during the second half of an NFL football game against the Arizona Cardinals, Sunday, Sept. 11, 2022, in Glendale, Ariz. (AP Photo/Matt York)

Kansas City Chiefs head coach Andy Reid watches during the second half of an NFL football game against the Arizona Cardinals, Sunday, Sept. 11, 2022, in Glendale, Ariz. (AP Photo/Matt York)

Sep. 11, 2022 07:28 PM EDT
Kansas City Chiefs quarterback Patrick Mahomes (15) throws against the Arizona Cardinals during the first half of an NFL football game, Sunday, Sept. 11, 2022, in Glendale, Ariz. (AP Photo/Matt York)

Kansas City Chiefs quarterback Patrick Mahomes (15) throws against the Arizona Cardinals during the first half of an NFL football game, Sunday, Sept. 11, 2022, in Glendale, Ariz. (AP Photo/Matt York)

Sep. 11, 2022 04:54 PM EDT
Kansas City Chiefs tight end Travis Kelce (87) catches a pass for a touchdown against Arizona Cardinals linebacker Isaiah Simmons (9) during the first half of an NFL football game, Sunday, Sept. 11, 2022, in Glendale, Ariz. (AP Photo/Ross D. Franklin)

Kansas City Chiefs tight end Travis Kelce (87) catches a pass for a touchdown against Arizona Cardinals linebacker Isaiah Simmons (9) during the first half of an NFL football game, Sunday, Sept. 11, 2022, in Glendale, Ariz. (AP Photo/Ross D. Franklin)

Sep. 11, 2022 07:48 PM EDT
Kansas City Chiefs tight end Travis Kelce (87) runs against Arizona Cardinals' Nick Vigil during the first half of an NFL football game, Sunday, Sept. 11, 2022, in Glendale, Ariz. (AP Photo/Matt York)

Kansas City Chiefs tight end Travis Kelce (87) runs against Arizona Cardinals' Nick Vigil during the first half of an NFL football game, Sunday, Sept. 11, 2022, in Glendale, Ariz. (AP Photo/Matt York)

Sep. 11, 2022 05:30 PM EDT
Kansas City Chiefs running back Clyde Edwards-Helaire (25) celebrates after scoring a touchdown against the Arizona Cardinals during the first half of an NFL football game, Sunday, Sept. 11, 2022, in Glendale, Ariz. (AP Photo/Matt York)

Kansas City Chiefs running back Clyde Edwards-Helaire (25) celebrates after scoring a touchdown against the Arizona Cardinals during the first half of an NFL football game, Sunday, Sept. 11, 2022, in Glendale, Ariz. (AP Photo/Matt York)

Sep. 11, 2022 05:01 PM EDT
Arizona Cardinals quarterback Kyler Murray (1) walks off the field after a loss to the Kansas City Chiefs in an NFL football game, Sunday, Sept. 11, 2022, in Glendale, Ariz. (AP Photo/Ross D. Franklin)

Arizona Cardinals quarterback Kyler Murray (1) walks off the field after a loss to the Kansas City Chiefs in an NFL football game, Sunday, Sept. 11, 2022, in Glendale, Ariz. (AP Photo/Ross D. Franklin)

Sep. 11, 2022 07:39 PM EDT
Kansas City Chiefs tight end Travis Kelce (87) and wide receiver JuJu Smith-Schuster (9) celebrate Kelce's touchdown against the Arizona Cardinals during the first half of an NFL football game, Sunday, Sept. 11, 2022, in Glendale, Ariz. (AP Photo/Matt York)

Kansas City Chiefs tight end Travis Kelce (87) and wide receiver JuJu Smith-Schuster (9) celebrate Kelce's touchdown against the Arizona Cardinals during the first half of an NFL football game, Sunday, Sept. 11, 2022, in Glendale, Ariz. (AP Photo/Matt York)

Sep. 11, 2022 04:53 PM EDT